https://www.ceesdekker.net - An Overview
https://www.ceesdekker.net - An Overview
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Around the exact time, the group of Paul McEuen, who was then based within the College of California, Berkeley, showed similar effects on ropes of bundled nanotubes. Dependant upon the wrapping angle, nanotubes can are available in metallic or semiconducting variants, a prediction that we and Charles Lieber’s team at Harvard University independently verified employing scanning tunnelling spectroscopy experiments.
Non-equilibrium folding of unique DNA molecules recaptured nearly a thousand periods in a very stable point out nanopore
We develop issue-of-treatment diagnostics check of neglected tropical illnesses in just source-constrained settings, dependant on Crspr/Cas9 detecting of pathogen’s DNA in overall body fluids.
Within the many years subsequent these discoveries, my research pursuits shifted to biophysics and nanobiology, And that i grew to become significantly less involved in the event of nanotube electronics. The main focus of many researchers in the field also shifted to graphene (where by, funnily plenty of, the primary graphene ribbons have been described as ‘nanotubes that are Slash open up along their duration’) immediately after the discovery of the two-dimensional product in 2004.
MATLAB codes for knowledge processing are available at . Julia codes useful for numerical simulation can be obtained at .
Atomic power microscopy demonstrates that vaccinia topoisomerase IB generates filaments on DNA in a cooperative trend
Comprehending basic processes regulating the spatial and dynamic organisation in the DNA in Dwell cells.
‘The fantastically refined way through which aspects in character perform never ceases to amaze me. If we address the puzzle of how everyday living came into currently being, I count on that my amazement in the complexity of creation should have enhanced and with it my awe for the greatness of your Creator.’
Given that 2000 he moved to single-molecule biophysics and nanobiology, with exploration from scientific studies of DNA loop extrusion and supercoiling to DNA translocation via nanopores. Extra just lately his study has centered on learning chromatin structure and mobile division with bacteria on chip, when he is additionally seeking to in ceesdekker the end Establish synthetic cells from The underside up.
Cees Dekker is Distinguished University Professor at TU Delft. Skilled being a physicist, he pioneered nanotechnology with a lot of discoveries on carbon nanotubes from the nineties. Due to the fact 2000, he moved to solitary-molecule biophysics and nanobiology. His recent investigation focuses on (i) nanopores for protein sequencing; (ii) chromosome construction, particularly SMC motor protein; and (iii) building a living artificial mobile from lifeless molecules. Dekker is really an elected member on the KNAW and fellow on the APS along with the IOP.
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Illustration (2) of bending configurations in 3D simulations of DNA rods on nanopores. A percentage of the membrane is proven in grey, the rim of your pore is highlighted in crimson, and a 3D rendering with the motion with the DNA rod is displayed.